MolNFT v1 · #187196 · protein + DNA + RNA
CAS9:GRNA in complex with 18-20MM DNA, 1 minute time-point, kinked active conformation
7S4X: “CAS9:GRNA in complex with 18-20MM DNA, 1 minute time-point, kinked active conformation”. Electron microscopy, 1 ligand (MG). MolNFT v1 #187196 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7S4X
- Type
- protein + DNA + RNA
- Length
- 1,515 residues
- Chains
- 5
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q99ZW2
- Ligands
- MG
Structure
electron microscopy · 5 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 1354 | — | Q99ZW2 |
| B | — | rna | 98 | — | — |
| C | — | dna | 16 | — | — |
| c | — | dna | 20 | — | — |
| D | — | dna | 27 | — | — |
Ligands and binding sites
- MG · Magnesium ion · metal · 5 copies · chains A, D, C, c, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7S4X · Cas9:gRNA in complex with 18-20MM DNA, 1 minute time-point, kinked active conformation · the same entry in another collection · chain B against B, TM-score 1.00
- Q99ZW2 · AlphaFold monomer V2.0 prediction for CRISPR-associated endonuclease CAS9/CSN1 (Q99ZW2) · a predicted model of the same protein · chain A against A, TM-score 0.84
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q99ZW2
- Elsewhere: RCSB PDB 7S4X · PDBe 7S4X · UniProt Q99ZW2
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