MolNFT v1 · #187100 · protein

Glp-1 receptor bound with pfizer small molecule agonist

7S15: “Glp-1 receptor bound with pfizer small molecule agonist”. Electron microscopy, 1 ligand (82L). MolNFT v1 #187100 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7S15
Type: protein
Length: 382 residues
Chains: 1
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P43220
Ligands: 82L

Structure

electron microscopy · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
R	—	protein	382	—	P43220

Ligands and binding sites

82L · 2-[(4-{6-[(2,4-difluorophenyl)methoxy]pyridin-2-yl}piperidin-1-yl)methyl]-1-[(1-ethyl-1H-imidazol-5-yl)methyl]-1H-benzimidazole-6-carboxylic acid · ligand · chains R

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7S15 · GLP-1 receptor bound with Pfizer small molecule agonist · the same entry in another collection · chain R against R, TM-score 1.00
P43220 · AlphaFold monomer V2.0 prediction for glucagon-like peptide 1 receptor (P43220) · a predicted model of the same protein · chain R against A, TM-score 0.81

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P43220
Elsewhere: RCSB PDB 7S15 · PDBe 7S15 · UniProt P43220

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