MolNFT v1 · #187014 · protein
Human methionine adenosyltransferase 2A bound to methylthioadenosine and two sulfate in the active site
7RXX: “Human methionine adenosyltransferase 2A bound to methylthioadenosine and two sulfate in the active site”. X-ray diffraction, 6 ligands (MTA, P3G, NA). MolNFT v1 #187014 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7RXX
- Type
- protein
- Length
- 381 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P31153
- Ligands
- MTA, P3G, NA, MG, K, SO4
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 381 | — | P31153 |
Ligands and binding sites
- MTA · 5'-deoxy-5'-methylthioadenosine · ligand · chains A
- P3G · 3,6,9,12,15-pentaoxaheptadecane · ligand · chains A
- NA · Sodium ion · metal · 4 copies · chains A
- MG · Magnesium ion · metal · 2 copies · chains A
- K · Potassium ion · metal · chains A
- SO4 · Sulfate ion · ion · 2 copies · chains A
- EDO · 1,2-ethanediol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7RXX · Human Methionine Adenosyltransferase 2A bound to Methylthioadenosine and two sulfate in… · the same entry in another collection · chain A against A, TM-score 1.00
- P31153 · AlphaFold monomer V2.0 prediction for S-adenosylmethionine synthase isoform type-2… · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P31153
- Elsewhere: RCSB PDB 7RXX · PDBe 7RXX · UniProt P31153
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