MolNFT v1 · #187007 · protein
Crystal structure of junctophilin-2 in complex with a CAV1.1 peptide
7RXQ · Junctophilin-2 N-terminal fragment: “Crystal structure of junctophilin-2 in complex with a CAV1.1 peptide”. X-ray diffraction, 1 ligand (SO4). MolNFT v1 #187007 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7RXQ
- Type
- protein
- Length
- 290 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Junctophilin-2 N-terminal fragment; Voltage-dependent L-type calcium channel subunit…
- UniProt
- Q9BR39, P07293
- Ligands
- SO4
Structure
x-ray diffraction · 2 distinct chains · 23% helix, 47% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Junctophilin-2 N-terminal fragment | protein | 275 | 24% helix, 49% strand | Q9BR39 |
| B | Voltage-dependent L-type calcium channel subunit alpha-1S | protein | 15 | 0% helix, 0% strand | P07293 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- A–B · 820 Ų buried · 17 hydrogen bonds · protein-protein
Compared structures
- 7RXQ · Crystal structure of junctophilin-2 in complex with a CaV1.1 peptide · the same entry in another collection · chain A against A, TM-score 1.00
- Q9BR39 · AlphaFold monomer V2.0 prediction for junctophilin-2 (Q9BR39) · a predicted model of the same protein · chain A against A, TM-score 0.96
- P07293 · AlphaFold monomer V2.0 prediction for voltage-dependent L-type calcium channel subunit… · a predicted model of the same protein · chain B against A, TM-score 0.22
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9BR39
- Every structure of UniProt P07293
- Elsewhere: RCSB PDB 7RXQ · PDBe 7RXQ · UniProt Q9BR39 · UniProt P07293
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