MolNFT v1 · #187005 · protein
Crystal structure of CDK2 liganded with compound WN333
7RXO · Cyclin-dependent kinase 2: “Crystal structure of CDK2 liganded with compound WN333”. X-ray diffraction, 1 ligand (80E), 1 pocket (best druggability 0.67). MolNFT v1 #187005 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 7RXO
- Type
- protein
- Length
- 266 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cyclin-dependent kinase 2
- EC
- 2.7.11.22
- UniProt
- P24941
- Ligands
- 80E
- Pockets
- 1 · best druggability 0.67
Structure
x-ray diffraction · 1 distinct chain · 36% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cyclin-dependent kinase 2 (EC 2.7.11.22) | protein | 266 | 36% helix, 15% strand | P24941 |
Ligands and binding sites
- 80E · 2-{[2-(1H-indol-3-yl)ethyl]amino}-5-(methoxycarbonyl) benzoic acid · ligand · chains A
- EDO · 1,2-ethanediol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 385 | 0.67 | 0.80 | 48 | 80E |
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P24941
- Elsewhere: RCSB PDB 7RXO · PDBe 7RXO · UniProt P24941
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.