MolNFT v1 · #186927 · protein
Crystal structure of the BCL6 btb domain in complex with oicr-9322
7RV7 · Isoform 2 of B-cell lymphoma 6 protein: “Crystal structure of the BCL6 btb domain in complex with oicr-9322”. X-ray diffraction, 2 ligands (7SH, CA). MolNFT v1 #186927 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7RV7
- Type
- protein
- Length
- 123 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Isoform 2 of B-cell lymphoma 6 protein
- UniProt
- P41182
- Ligands
- 7SH, CA
Structure
x-ray diffraction · 1 distinct chain · 53% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Isoform 2 of B-cell lymphoma 6 protein | protein | 123 | 53% helix, 11% strand | P41182 |
Ligands and binding sites
- 7SH · N-(3-chloropyridin-4-yl)-2-{5-(3-cyano-4-hydroxyphenyl)-3-[3-(1-methyl-1H-pyrazol-4-yl)prop-2-yn-1-yl]-4-oxo-3,4-dihydro-7H-pyrrolo[2,3-d]pyrimidin-7-yl}acetamide · ligand · chains A
- CA · Calcium ion · metal · chains A
- GOL · Glycerol · additive · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7RV7 · Crystal structure of the BCL6 BTB domain in complex with OICR-9322 · the same entry in another collection · chain A against A, TM-score 1.00
- P41182 · AlphaFold monomer V2.0 prediction for B-cell lymphoma 6 protein (P41182) · a predicted model of the same protein · chain A against A, TM-score 0.31
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P41182
- Elsewhere: RCSB PDB 7RV7 · PDBe 7RV7 · UniProt P41182
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