MolNFT v1 · #186895 · protein
X-ray crystallographic structure of a beta-hairpin peptide derived from amyloid beta 14-40
7RTZ · Amyloid-beta protein 40: “X-ray crystallographic structure of a beta-hairpin peptide derived from amyloid beta 14-40”. X-ray diffraction, 1 ligand (CL). MolNFT v1 #186895 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7RTZ
- Type
- protein
- Length
- 48 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Amyloid-beta protein 40
- UniProt
- P05067
- Ligands
- CL
Structure
x-ray diffraction · 1 distinct chain · 0% helix, 75% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Amyloid-beta protein 40 | protein | 24 | 0% helix, 75% strand | P05067 |
Ligands and binding sites
- CL · Chloride ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- A–B · 250 Ų buried · 4 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 6 modified, 2 disulfide (nonstandard, disulfide, methylation).
Compared structures
- 7RTZ · X-ray crystallographic structure of a beta-hairpin peptide derived from amyloid beta 14-40 · the same entry in another collection · chain A against A, TM-score 1.00
- P05067 · AlphaFold monomer V2.0 prediction for amyloid-beta precursor protein (P05067) · a predicted model of the same protein · chain B against A, TM-score 0.35
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P05067
- Elsewhere: RCSB PDB 7RTZ · PDBe 7RTZ · UniProt P05067
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.