MolNFT v1 · #186829 · protein

Crystal structure of human 0606T1-2 TCR bound to HLA-A*03:01 in complex with a mutant PIK3CA peptide

7RRG: “Crystal structure of human 0606T1-2 TCR bound to HLA-A*03:01 in complex with a mutant PIK3CA peptide”. X-ray diffraction. MolNFT v1 #186829 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7RRG
Type: protein
Length: 803 residues
Chains: 5
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P04439, P61769, P42336

Structure

x-ray diffraction · 5 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	272	—	P04439
B	—	protein	100	—	P61769
D	—	protein	185	—	—
E	—	protein	237	—	—
C	—	protein	9	—	P42336

Ligands and binding sites

GOL · Glycerol · additive · 13 copies · chains A, B, D, E, C

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7RRG · Crystal structure of human 0606T1-2 TCR bound to HLA-A*03:01 in complex with a mutant… · the same entry in another collection · chain B against B, TM-score 1.00
P04439 · AlphaFold monomer V2.0 prediction for HLA class I histocompatibility antigen, a alpha… · a predicted model of the same protein · chain A against A, TM-score 0.99
P61769 · AlphaFold monomer V2.0 prediction for beta-2-microglobulin (P61769) · a predicted model of the same protein · chain B against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P04439
Every structure of UniProt P61769
Every structure of UniProt P42336
Elsewhere: RCSB PDB 7RRG · PDBe 7RRG · UniProt P04439 · UniProt P61769 · UniProt P42336

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