MolNFT v1 · #186599 · protein
Crystal structure of AP2 associated kinase 1 isoform 1 complexed with ligand 2-(1-amino-3-methylbutyl)-6- (pyridin-4-YL)QUINOLINE-4- carbonitrile
7RJ7: “Crystal structure of AP2 associated kinase 1 isoform 1 complexed with ligand 2-(1-amino-3-methylbutyl)-6…”. X-ray diffraction, 2 ligands (5P6, SO4). MolNFT v1 #186599 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7RJ7
- Type
- protein
- Length
- 604 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q3UHJ0
- Ligands
- 5P6, SO4
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 304 | — | Q3UHJ0 |
| B | — | protein | 300 | — | Q3UHJ0 |
Ligands and binding sites
- 5P6 · 2-[(1S)-1-amino-3-methylbutyl]-6-(pyridin-4-yl) quinoline-4-carbonitrile · ligand · 2 copies · chains A, B
- SO4 · Sulfate ion · ion · 6 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7RJ7 · Crystal structure of AP2 associated kinase 1 isoform 1 complexed with ligand… · the same entry in another collection · chain A against A, TM-score 1.00
- Q3UHJ0 · AlphaFold monomer V2.0 prediction for AP2-associated protein kinase 1 (Q3UHJ0) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q3UHJ0
- Elsewhere: RCSB PDB 7RJ7 · PDBe 7RJ7 · UniProt Q3UHJ0
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