MolNFT v1 · #186505 · protein

Importin ALPHA3 in complex with P50 nls

7RG5 · Importin subunit alpha-3: “Importin ALPHA3 in complex with P50 nls”. X-ray diffraction. MolNFT v1 #186505 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7RG5
Type: protein
Length: 424 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Importin subunit alpha-3; Isoform 3 of nuclear factor nf-kappa-B P105 subunit
UniProt: O00629

Structure

x-ray diffraction · 2 distinct chains · 74% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Importin subunit alpha-3	protein	416	75% helix, 0% strand	O00629
B	Isoform 3 of nuclear factor nf-kappa-B P105 subunit	protein	8	0% helix, 0% strand	—

Interfaces

1 interface between chains.

A–B · 742 Å² buried · 18 hydrogen bonds · protein-protein

Compared structures

7RG5 · Importin alpha3 in complex with p50 NLS · the same entry in another collection · chain A against A, TM-score 1.00
O00629 · AlphaFold monomer V2.0 prediction for importin subunit alpha-3 (O00629) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O00629
Elsewhere: RCSB PDB 7RG5 · PDBe 7RG5 · UniProt O00629

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