MolNFT v1 · #186469 · protein

Human IMPDH1 treated with ATP, imp, and NAD+

7RER: “Human IMPDH1 treated with ATP, imp, and NAD+”. Electron microscopy, 2 ligands (NAD, IMP). MolNFT v1 #186469 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7RER
Type: protein
Length: 3,112 residues
Chains: 8
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P20839
Ligands: NAD, IMP

Structure

electron microscopy · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, D, C, B, E, H, G, F	—	protein	389	—	P20839

Ligands and binding sites

NAD · Nicotinamide-adenine-dinucleotide · ligand · 8 copies · chains A, B, D, C, E, F, H, G
IMP · Inosinic acid · ligand · 8 copies · chains A, D, C, B, E, H, G, F

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7RER · Human IMPDH1 treated with ATP, imp, and NAD+ · the same entry in another collection · chain F against F, TM-score 1.00
P20839 · AlphaFold monomer V2.0 prediction for inosine-5'-monophosphate dehydrogenase 1 (P20839) · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P20839
Elsewhere: RCSB PDB 7RER · PDBe 7RER · UniProt P20839

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