MolNFT v1 · #186383 · protein
Aeronamide N-methyltransferase, aere (N231A)
7RC5 · Methyltransferase family protein: “Aeronamide N-methyltransferase, aere (N231A)”. X-ray diffraction, 2 ligands (SAH, CA), 3 pockets (best druggability 0.75). MolNFT v1 #186383 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 7RC5
- Type
- protein
- Length
- 375 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Methyltransferase family protein
- UniProt
- A0A329B7M1
- Ligands
- SAH, CA
- Pockets
- 3 · best druggability 0.75
Structure
x-ray diffraction · 1 distinct chain · 41% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Methyltransferase family protein | protein | 375 | 41% helix, 23% strand | A0A329B7M1 |
Ligands and binding sites
- SAH · S-adenosyl-L-homocysteine · ligand · chains A
- CA · Calcium ion · metal · chains A
- PGE · Triethylene glycol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 679 | 0.75 | 0.81 | 76 | SAH |
| 2 | 78 | 0.32 | 0.74 | 20 | empty |
| 3 | 50 | 0.31 | 0.77 | 12 | empty |
Compared structures
- 7RC5 · Aeronamide N-methyltransferase, AerE (N231A) · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A329B7M1
- Elsewhere: RCSB PDB 7RC5 · PDBe 7RC5 · UniProt A0A329B7M1
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.