MolNFT v1 · #186249 · protein
Structure of human SHP2 in complex with compound 30
7R7L: “Structure of human SHP2 in complex with compound 30”. X-ray diffraction, 1 ligand (3ED). MolNFT v1 #186249 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7R7L
- Type
- protein
- Length
- 979 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q06124
- Ligands
- 3ED
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 490 | — | Q06124 |
| B | — | protein | 489 | — | Q06124 |
Ligands and binding sites
- 3ED · 6-[(3S,4S)-4-amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]-3-(2,3-dichlorophenyl)-2-methylpyrimidin-4(3H)-one · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7R7L · Structure of human SHP2 in complex with compound 30 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q06124
- Elsewhere: RCSB PDB 7R7L · PDBe 7R7L · UniProt Q06124
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