MolNFT v1 · #186229 · protein

E117K mutant pyruvate kinase from rabbit muscle

7R6Y: “E117K mutant pyruvate kinase from rabbit muscle”. X-ray diffraction, 2 ligands (OXL, MG). MolNFT v1 #186229 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7R6Y
Type: protein
Length: 1,897 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P11974
Ligands: OXL, MG

Structure

x-ray diffraction · 3 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	—	protein	519	—	P11974
C	—	protein	437	—	P11974
D	—	protein	422	—	P11974

Ligands and binding sites

OXL · Oxalate ion · ligand · 4 copies · chains A, B, C, D
MG · Magnesium ion · metal · 4 copies · chains A, B, C, D
ACT · Acetate ion · additive · 9 copies · chains A, B, C, D

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7R6Y · E117K mutant pyruvate kinase from rabbit muscle · the same entry in another collection · chain A against A, TM-score 1.00
P11974 · AlphaFold monomer V2.0 prediction for pyruvate kinase pkm (P11974) · a predicted model of the same protein · chain D against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P11974
Elsewhere: RCSB PDB 7R6Y · PDBe 7R6Y · UniProt P11974

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