MolNFT v1 · #186173 · protein
Rvx-inhibited acetylcholinesterase in complex with 2-((hydroxyimino) methyl)-1-(5-(4-methyl-3-NITROBENZAMIDO)PENTYL)PYRIDINIUM
7R4E: “Rvx-inhibited acetylcholinesterase in complex with 2-((hydroxyimino)…”. X-ray diffraction, 4 ligands (TOE, I1X, P15). MolNFT v1 #186173 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7R4E
- Type
- protein
- Length
- 1,070 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P21836
- Ligands
- TOE, I1X, P15, NAG
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 537 | — | P21836 |
| B | — | protein | 533 | — | P21836 |
Ligands and binding sites
- TOE · 2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxyl · ligand · 3 copies · chains A, B
- I1X · 4-methyl-3-nitro-~{N}-[(2~{E},4~{E})-5-[2-[(oxidanylamino)methyl]pyridin-1-yl]penta-2,4-dienyl]benzamide · ligand · 2 copies · chains A, B
- P15 · 2,5,8,11,14,17-hexaoxanonadecan-19-ol · ligand · chains A, B
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 4 copies · chains A, B
- PG0 · 2-(2-methoxyethoxy)ethanol · additive · 5 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P21836
- Elsewhere: RCSB PDB 7R4E · PDBe 7R4E · UniProt P21836
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