MolNFT v1 · #186122 · protein
KRASG12C in complex with GDP and compound 3
7R0Q: “KRASG12C in complex with GDP and compound 3”. X-ray diffraction, 3 ligands (H0O, GDP, MG). MolNFT v1 #186122 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7R0Q
- Type
- protein
- Length
- 334 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P01116
- Ligands
- H0O, GDP, MG
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 168 | — | P01116 |
| B | — | protein | 166 | — | P01116 |
Ligands and binding sites
- H0O · ~{N}-[4-[3,5-dimethyl-4-(5-methyl-2~{H}-indazol-4-yl) pyrazol-1-yl]phenyl]propanamide · ligand · 2 copies · chains A, B
- GDP · Guanosine-5'-diphosphate · ligand · 2 copies · chains A, B
- MG · Magnesium ion · metal · 3 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7R0Q · KRasG12C in complex with GDP and compound 3 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P01116
- Elsewhere: RCSB PDB 7R0Q · PDBe 7R0Q · UniProt P01116
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