MolNFT v1 · #185749 · protein

Hisf from T. maritima

7QC3 · Imidazole glycerol phosphate synthase subunit hisf: “Hisf from T. maritima”. X-ray diffraction, 1 pocket (best druggability 0.66). MolNFT v1 #185749 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7QC3
Type: protein
Length: 249 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Imidazole glycerol phosphate synthase subunit hisf
EC: 4.3.2.10
UniProt: Q9X0C6
Pockets: 1 · best druggability 0.66

Structure

x-ray diffraction · 1 distinct chain · 41% helix, 25% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Imidazole glycerol phosphate synthase subunit hisf (EC 4.3.2.10)	protein	249	41% helix, 25% strand	Q9X0C6

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	403	0.66	0.79	46	empty

Compared structures

7QC3 · HisF from T. maritima · the same entry in another collection · chain A against A, TM-score 1.00
Q9X0C6 · AlphaFold monomer V2.0 prediction for imidazole glycerol phosphate synthase subunit hisf… · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9X0C6
Elsewhere: RCSB PDB 7QC3 · PDBe 7QC3 · UniProt Q9X0C6

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