MolNFT v1 · #185583 · protein

Arches protomer (trimer of TRWG/VIRB8PERI) structure from the fully- assembled R388 type IV secretion system determined by cryo-EM.

7Q1V · Trwg protein: “Arches protomer (trimer of TRWG/VIRB8PERI) structure from the fully- assembled R388 type IV secretion system…”. Electron microscopy, 3 pockets (best druggability 0.60). MolNFT v1 #185583 on GenesisL1: 3D structure…

PDB: 7Q1V
Type: protein
Length: 411 residues
Chains: 3
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Trwg protein
UniProt: O50335
Pockets: 3 · best druggability 0.60

Structure

electron microscopy · 1 distinct chain · 32% helix, 35% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
D, E, F	Trwg protein	protein	137	32% helix, 35% strand	O50335

Pockets

3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	601	0.60	0.74	77	empty
2	439	0.57	0.74	48	empty
3	433	0.56	0.74	58	empty

Interfaces

2 interfaces between chains.

D–E · 138 Å² buried · 7 hydrogen bonds · protein-protein
E–F · 84 Å² buried · 0 hydrogen bonds · protein-protein

Compared structures

7Q1V · Arches protomer (trimer of TrwG/VirB8peri) structure from the fully-assembled R388 type… · the same entry in another collection · chain D against D, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O50335
Elsewhere: RCSB PDB 7Q1V · PDBe 7Q1V · UniProt O50335

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