MolNFT v1 · #185459 · protein
Structure of human dimeric acmsd in complex with the inhibitor tes- 1025
7PWY: “Structure of human dimeric acmsd in complex with the inhibitor tes- 1025”. X-ray diffraction, 3 ligands (8EK, K, ZN). MolNFT v1 #185459 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7PWY
- Type
- protein
- Length
- 1,289 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q8TDX5
- Ligands
- 8EK, K, ZN
Structure
x-ray diffraction · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | — | protein | 334 | — | Q8TDX5 |
| C | — | protein | 301 | — | Q8TDX5 |
| D | — | protein | 320 | — | Q8TDX5 |
Ligands and binding sites
- 8EK · 2-[3-[(5-cyano-6-oxidanylidene-4-thiophen-2-yl-1H-pyrimidin-2-yl)sulfanylmethyl]phenyl]ethanoic acid · ligand · 2 copies · chains A, B
- K · Potassium ion · metal · 6 copies · chains A, B, C, D
- ZN · Zinc ion · metal · 4 copies · chains A, B, C, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7PWY · Structure of human dimeric ACMSD in complex with the inhibitor TES-1025 · the same entry in another collection · chain D against D, TM-score 1.00
- Q8TDX5 · AlphaFold monomer V2.0 prediction for 2-amino-3-carboxymuconate-6-semialdehyde… · a predicted model of the same protein · chain C against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8TDX5
- Elsewhere: RCSB PDB 7PWY · PDBe 7PWY · UniProt Q8TDX5
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