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MolNFT v1 · #185260 · protein

Cryo-EM structure of the actomyosin-V complex in the post-rigor transition state (appnhp, central 1ER, class 5)

7PMI: “Cryo-EM structure of the actomyosin-V complex in the post-rigor transition state (appnhp, central 1ER, class…”. Electron microscopy, 3 ligands (ANP, ADP, MG). MolNFT v1 #185260 on GenesisL1: 3D structure, binding sites and pockets…

PDB
7PMI
Type
protein
Length
1,265 residues
Chains
4
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
Q02440, P68135, P14649
Ligands
ANP, ADP, MG

Structure

electron microscopy · 4 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein747—Q02440
C—protein372—P68135
H—protein7——
B—protein139—P14649

Ligands and binding sites

  • ANP · Phosphoaminophosphonic acid-adenylate ester · ligand · chains A
  • ADP · Adenosine-5'-diphosphate · ligand · chains C
  • MG · Magnesium ion · metal · 3 copies · chains A, C

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 7PMI · Cryo-EM structure of the actomyosin-V complex in the post-rigor transition state (AppNHp… · the same entry in another collection · chain A against A, TM-score 1.00
  • P68135 · AlphaFold monomer V2.0 prediction for actin, alpha skeletal muscle (P68135) · a predicted model of the same protein · chain C against A, TM-score 0.96
  • P14649 · AlphaFold monomer V2.0 prediction for myosin light chain 6B (P14649) · a predicted model of the same protein · chain B against A, TM-score 0.95
  • Q02440 · AlphaFold monomer V2.0 prediction for unconventional myosin-va (Q02440) · a predicted model of the same protein · chain A against A, TM-score 0.94

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