GL1X · GenesisL1 explorer

MolNFT v1 · #185201 · protein

Cereblon isoform 4 from magnetospirillum gryphiswaldense in complex with a benzotriazole analog of thalidomide

7PJK: “Cereblon isoform 4 from magnetospirillum gryphiswaldense in complex with a benzotriazole analog of thalidomide”. X-ray diffraction, 2 ligands (7SE, ZN). MolNFT v1 #185201 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
7PJK
Type
protein
Length
265 residues
Chains
3
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
A4TVL0
Ligands
7SE, ZN

Structure

x-ray diffraction · 2 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A, B—protein105—A4TVL0
C—protein55—A4TVL0

Ligands and binding sites

  • 7SE · (3S)-3-(benzotriazol-2-yl)piperidine-2,6-dione · ligand · 2 copies · chains A, B
  • ZN · Zinc ion · metal · 3 copies · chains A, B, C

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 7PJK · Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with a benzotriazole… · the same entry in another collection · chain A against A, TM-score 1.00

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