Epstein-barr virus encoded apoptosis regulator BHRF1 in complex with puma BH3

Structure

x-ray diffraction · 2 distinct chains · 77% helix, 0% strand (DSSP).

Ligands and binding sites

• MG · Magnesium ion · metal · 5 copies · chains A
• CL · Chloride ion · ion · 6 copies · chains A, B
• PO4 · Phosphate ion · ion · 3 copies · chains A
• NH4 · Ammonium ion · ion · chains A
• EDO · 1,2-ethanediol · additive · 6 copies · chains A, B
• PDO · 1,3-propandiol · additive · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

• A–B · 883 Ų buried · 3 hydrogen bonds · protein-protein

Compared structures

• 7P9W · Epstein-Barr virus encoded apoptosis regulator BHRF1 in complex with Puma BH3 · the same entry in another collection · chain A against A, TM-score 1.00
• Q9BXH1 · AlphaFold monomer V2.0 prediction for BCL-2-binding component 3, isoforms 1/2 (Q9BXH1) · a predicted model of the same protein · chain B against A, TM-score 0.69

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P03182
• Every structure of UniProt Q9BXH1
• Elsewhere: RCSB PDB 7P9W · PDBe 7P9W · UniProt P03182 · UniProt Q9BXH1