UniProt Q9BXH1
Bcl-2-binding component 3 (Q9BXH1)
Bcl-2-binding component 3 (UniProt Q9BXH1): 16 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9BXH1
- Protein
- Bcl-2-binding component 3
- Experimental structures
- 16
- Predicted models
- 1
- Ligands
- 5
Structures
17 records of Q9BXH1 in the MolNFT archive: 16 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2M04 | Solution structure of BCL-xL in complex with PUMA BH3 peptide | solution nmr | B | — | — |
| 2M04 | Solution structure of BCL-xl in complex with puma BH3 peptide | solution nmr | B | — | — |
| 4HNJ | Crystallographic structure of BCL-xL domain-swapped dimer in complex with PUMA BH3 peptide at 2.9A… | x-ray diffraction | C | — | — |
| 4HNJ | Crystallographic structure of BCL-xl domain-swapped dimer in complex with puma BH3 peptide at 2.9A… | x-ray diffraction | C | — | — |
| 5UUL | Human Bfl-1 in complex with PUMA BH3 | x-ray diffraction | B | SO4 | — |
| 5UUL | Human bfl-1 in complex with puma BH3 | x-ray diffraction | B | ACE, NH2, SO4 | — |
| 6QFM | Structure of human Mcl-1 in complex with PUMA BH3 peptide | x-ray diffraction | B | ZN, CL | — |
| 6QFM | Structure of human mcl-1 in complex with puma BH3 peptide | x-ray diffraction | B | CL | — |
| 6QG8 | Structure of human Bcl-2 in complex with PUMA BH3 peptide | x-ray diffraction | B | — | — |
| 6QG8 | Structure of human BCL-2 in complex with puma BH3 peptide | x-ray diffraction | B | — | — |
| 6TQP | Structural insight into tanapoxvirus mediated inhibition of apoptosis | x-ray diffraction | B | — | — |
| 6TQP | Structural insight into tanapoxvirus mediated inhibition of apoptosis | x-ray diffraction | B | — | — |
| 7DVD | The crystal structure of P53 DNA binding domain and puma complex | x-ray diffraction | E | — | — |
| 7P0S | Orf virus encoded BCL-2 homolog ORFV125 in complex with puma BH3 peptide | x-ray diffraction | U, C | — | — |
| 7P9W | Epstein-barr virus encoded apoptosis regulator BHRF1 in complex with puma BH3 | x-ray diffraction | B | — | — |
| 7QTX | Kaposi sarcoma associated herpes virus (KSHV) encoded apoptosis inhibitor, KsBcl-2 in complex with… | x-ray diffraction | B | — | — |
| Q9BXH1 | AlphaFold monomer V2.0 prediction for BCL-2-binding component 3, isoforms 1/2 (Q9BXH1) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6QG8 chain B against the predicted model Q9BXH1: TM-score 0.79, RMSD 0.31 Å
- 6QG8 chain B against the predicted model Q9BXH1: TM-score 0.79, RMSD 0.31 Å
- 6QFM chain B against the predicted model Q9BXH1: TM-score 0.72, RMSD 0.34 Å
- 6QFM chain B against the predicted model Q9BXH1: TM-score 0.72, RMSD 0.34 Å
- 7P0S chain C against the predicted model Q9BXH1: TM-score 0.71, RMSD 0.73 Å
- 7P0S chain U against the predicted model Q9BXH1: TM-score 0.71, RMSD 0.88 Å
- 7P9W chain B against the predicted model Q9BXH1: TM-score 0.69, RMSD 0.40 Å
- 7QTX chain B against the predicted model Q9BXH1: TM-score 0.69, RMSD 0.81 Å
- 6TQP chain B against the predicted model Q9BXH1: TM-score 0.69, RMSD 1.50 Å
- 6TQP chain B against the predicted model Q9BXH1: TM-score 0.69, RMSD 1.50 Å
Elsewhere
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