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MolNFT v1 · #184736 · protein

Orf virus encoded BCL-2 homolog ORFV125 in complex with puma BH3 peptide

7P0U: “Orf virus encoded BCL-2 homolog ORFV125 in complex with puma BH3 peptide”. X-ray diffraction. MolNFT v1 #184736 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
7P0U
Type
protein
Length
616 residues
Chains
8
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
A0A0R8HV90, O00198

Structure

x-ray diffraction · 8 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein134—A0A0R8HV90
U—protein26—O00198
B—protein132—A0A0R8HV90
C—protein24—O00198
D—protein128—A0A0R8HV90
E—protein22—O00198
F—protein129—A0A0R8HV90
G—protein21—O00198

Ligands and binding sites

  • EDO · 1,2-ethanediol · additive · 5 copies · chains A, B, F
  • GOL · Glycerol · additive · 3 copies · chains A, C

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 7P0U · ORF virus encoded Bcl-2 homolog ORFV125 in complex with Puma BH3 peptide · the same entry in another collection · chain G against G, TM-score 1.00
  • O00198 · AlphaFold monomer V2.0 prediction for activator of apoptosis harakiri (O00198) · a predicted model of the same protein · chain E against A, TM-score 0.82

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