UniProt O00198
Activator of apoptosis harakiri (O00198)
Activator of apoptosis harakiri (UniProt O00198): 8 experimental structures and 1 predicted model on GenesisL1, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O00198
- Protein
- Activator of apoptosis harakiri
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 5 · 1 record with a druggable one
Structures
9 records of O00198 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2L58 | Solution structure of the cytosolic fragment 22-53 of Bcl-2 member Harakiri | solution nmr | A | — | — |
| 2L58 | Solution structure of the cytosolic fragment 22-53 of BCL-2 member harakiri | solution nmr | A | — | — |
| 2L5B | Solution structure of the transmembrane domain of Bcl-2 member Harakiri in micelles | solution nmr | A | — | — |
| 2L5B | Solution structure of the transmembrane domain of BCL-2 member harakiri in micelles | solution nmr | A | — | — |
| 6XY4 | Structural insight into sheep-pox virus mediated inhibition of apoptosis | x-ray diffraction | B | — | — |
| 6XY4 | Structural insight into sheep-pox virus mediated inhibition of apoptosis | x-ray diffraction | B | — | — |
| 7P0U | ORF virus encoded Bcl-2 homolog ORFV125 in complex with Puma BH3 peptide | x-ray diffraction | U, C, E, G | — | 5 (best 0.53) |
| 7P0U | Orf virus encoded BCL-2 homolog ORFV125 in complex with puma BH3 peptide | x-ray diffraction | U, C, E, G | — | — |
| O00198 | AlphaFold monomer V2.0 prediction for activator of apoptosis harakiri (O00198) | predicted | A | — | — |
Experiment against prediction
- 7P0U chain E against the predicted model O00198: TM-score 0.82, RMSD 0.35 Å
- 7P0U chain E against the predicted model O00198: TM-score 0.82, RMSD 0.35 Å
- 7P0U chain C against the predicted model O00198: TM-score 0.79, RMSD 0.47 Å
- 7P0U chain C against the predicted model O00198: TM-score 0.79, RMSD 0.47 Å
- 7P0U chain G against the predicted model O00198: TM-score 0.79, RMSD 0.35 Å
- 7P0U chain G against the predicted model O00198: TM-score 0.79, RMSD 0.35 Å
- 2L58 chain A against the predicted model O00198: TM-score 0.70, RMSD 1.28 Å
- 2L58 chain A against the predicted model O00198: TM-score 0.70, RMSD 1.28 Å
- 7P0U chain U against the predicted model O00198: TM-score 0.70, RMSD 1.39 Å
- 7P0U chain U against the predicted model O00198: TM-score 0.70, RMSD 1.39 Å
Elsewhere
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