MolNFT v1 · #184602 · protein
Protein kinase MKK7 in complex with phenethyltriazole-substituted pyrazolopyrimidine
7OVI: “Protein kinase MKK7 in complex with phenethyltriazole-substituted pyrazolopyrimidine”. X-ray diffraction, 1 ligand (2GI). MolNFT v1 #184602 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7OVI
- Type
- protein
- Length
- 262 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- O14733
- Ligands
- 2GI
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 262 | — | O14733 |
Ligands and binding sites
- 2GI · 1-[(3~{R})-3-[4-azanyl-3-[1-(2-phenylethyl)-1,2,3-triazol-4-yl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]propan-1-one · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7OVI · Protein kinase MKK7 in complex with phenethyltriazole-substituted pyrazolopyrimidine · the same entry in another collection · chain A against A, TM-score 1.00
- O14733 · AlphaFold monomer V2.0 prediction for dual specificity mitogen- activated protein kinase… · a predicted model of the same protein · chain A against A, TM-score 0.93
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O14733
- Elsewhere: RCSB PDB 7OVI · PDBe 7OVI · UniProt O14733
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.