GL1X · GenesisL1 explorer

Ligand · 2GI

2GI · 1-[(3~{R})-3-[4-azanyl-3-[1-(2-phenylethyl)-1,2,3-triazol-4-yl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]propan-1-one

2GI, 1-[(3~{R})-3-[4-azanyl-3-[1-(2-phenylethyl)-1,2,3-triazol-4-yl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]propan-1-one (C23 H27 N9 O, 445.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…

Component
2GI
Formula
C23 H27 N9 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

2GI in 2 structures; the first of them:

  • 7OVI · Protein kinase MKK7 in complex with phenethyltriazole-substituted pyrazolopyrimidine · 2GI A501 · binds MET142, GLY143, VAL150, ALA163, LYS165, ILE179, ASP182, LEU183 and 14 more
  • 7OVI · Protein kinase MKK7 in complex with phenethyltriazole-substituted pyrazolopyrimidine · 2GI A501 · binds MET142, GLY143, ALA163, LYS165, ILE179, ASP182, LEU183, VAL196 and 10 more

Residues it binds most

LEU 2, MET 2, ASP 2, GLU 2, ILE 2, LYS 2, VAL 2, CYS 2, ALA 2, GLY 2 (residue and the binding sites it lines).

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