MolNFT v1 · #184529 · protein + DNA
HIV-1 reverse transcriptase complex with DNA and inhibitor rmc-282
7OT6: “HIV-1 reverse transcriptase complex with DNA and inhibitor rmc-282”. X-ray diffraction, 2 ligands (1I4, MG). MolNFT v1 #184529 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7OT6
- Type
- protein + DNA
- Length
- 2,021 residues
- Chains
- 8
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P03366
- Ligands
- 1I4, MG
Structure
x-ray diffraction · 7 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| C | — | protein | 555 | — | P03366 |
| D | — | protein | 411 | — | P03366 |
| A | — | protein | 556 | — | P03366 |
| B | — | protein | 412 | — | P03366 |
| E | — | dna | 23 | — | — |
| F, P | — | dna | 20 | — | — |
| T | — | dna | 24 | — | — |
Ligands and binding sites
- 1I4 · (R)-N-(1-(6-amino-9H-purin-9-yl)propan-2-yl)-N-(2-phosphonoethyl)glycine · ligand · chains A, P, T
- MG · Magnesium ion · metal · chains A, P
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7OT6 · HIV-1 REVERSE TRANSCRIPTASE COMPLEX WITH DNA AND inhibitor RMC-282 · the same entry in another collection · chain C against C, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03366
- Elsewhere: RCSB PDB 7OT6 · PDBe 7OT6 · UniProt P03366
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