MolNFT v1 · #184470 · protein
Ternary complex of 14-3-3 sigma, NOTCHPS1917 phosphopeptide, and WQ178
7OR7: “Ternary complex of 14-3-3 sigma, NOTCHPS1917 phosphopeptide, and WQ178”. X-ray diffraction, 3 ligands (0B7, MG, CL). MolNFT v1 #184470 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7OR7
- Type
- protein
- Length
- 237 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P31947, Q99466
- Ligands
- 0B7, MG, CL
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 229 | — | P31947 |
| B | — | protein | 8 | — | Q99466 |
Ligands and binding sites
- 0B7 · ~{N}-[(5-carbamimidoyl-3-phenyl-thiophen-2-yl)methyl]-1~{H}-indole-6-carboxamide · ligand · chains A
- MG · Magnesium ion · metal · chains A
- CL · Chloride ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7OR7 · Ternary complex of 14-3-3 sigma, NotchpS1917 phosphopeptide, and WQ178 · the same entry in another collection · chain A against A, TM-score 1.00
- P31947 · AlphaFold monomer V2.0 prediction for 14-3-3 protein sigma (P31947) · a predicted model of the same protein · chain A against A, TM-score 0.96
- Q99466 · AlphaFold monomer V2.0 prediction for neurogenic locus notch homolog protein 4 (Q99466) · a predicted model of the same protein · chain B against A, TM-score 0.48
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P31947
- Every structure of UniProt Q99466
- Elsewhere: RCSB PDB 7OR7 · PDBe 7OR7 · UniProt P31947 · UniProt Q99466
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