MolNFT v1 · #184418 · protein
Trypanosoma brucei PTR1 (TBPTR1) in complex with pyrimethamine
7OPJ: “Trypanosoma brucei PTR1 (TBPTR1) in complex with pyrimethamine”. X-ray diffraction, 2 ligands (NAP, CP6). MolNFT v1 #184418 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7OPJ
- Type
- protein
- Length
- 990 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- O76290
- Ligands
- NAP, CP6
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 250 | — | O76290 |
| B | — | protein | 248 | — | O76290 |
| C | — | protein | 243 | — | O76290 |
| D | — | protein | 249 | — | O76290 |
Ligands and binding sites
- NAP · Nadp nicotinamide-adenine-dinucleotide phosphate · ligand · 4 copies · chains A, B, C, D
- CP6 · 5-(4-chloro-phenyl)-6-ethyl-pyrimidine-2,4-diamine · ligand · 4 copies · chains A, B, C, D
- ACT · Acetate ion · additive · 4 copies · chains A, B
- GOL · Glycerol · additive · chains C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7OPJ · Trypanosoma brucei PTR1 (TbPTR1) in complex with pyrimethamine · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O76290
- Elsewhere: RCSB PDB 7OPJ · PDBe 7OPJ · UniProt O76290
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