MolNFT v1 · #184259 · protein

Saftsz complexed with gmpcp

7OJZ · Cell division protein ftsz: “Saftsz complexed with gmpcp”. X-ray diffraction, 2 ligands (GP2, K), 3 pockets (best druggability 0.61). MolNFT v1 #184259 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7OJZ
Type: protein
Length: 307 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cell division protein ftsz
UniProt: P0A031
Ligands: GP2, K
Pockets: 3 · best druggability 0.61

Structure

x-ray diffraction · 1 distinct chain · 45% helix, 23% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Cell division protein ftsz	protein	307	45% helix, 23% strand	P0A031

Ligands and binding sites

GP2 · Phosphomethylphosphonic acid guanosyl ester · ligand · chains A
K · Potassium ion · metal · chains A
EDO · 1,2-ethanediol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	231	0.61	0.81	42	GP2, EDO
2	81	0.43	0.80	18	empty
3	62	0.41	0.80	16	empty

Compared structures

7OJZ · SaFtsZ complexed with GMPCP · the same entry in another collection · chain A against A, TM-score 1.00
P0A031 · AlphaFold monomer V2.0 prediction for cell division protein ftsz (P0A031) · a predicted model of the same protein · chain A against A, TM-score 0.88

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P0A031
Elsewhere: RCSB PDB 7OJZ · PDBe 7OJZ · UniProt P0A031

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