GL1X · GenesisL1 explorer

MolNFT v1 · #184196 · protein

Cryo-EM structure of DRS2P-CDC50P in the E1-amppcp state with PI4P bound

7OH7: “Cryo-EM structure of DRS2P-CDC50P in the E1-amppcp state with PI4P bound”. Electron microscopy, 5 ligands (2Y5, ACP, NAG). MolNFT v1 #184196 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
7OH7
Type
protein
Length
1,414 residues
Chains
2
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P39524, P25656
Ligands
2Y5, ACP, NAG, BMA, MG

Structure

electron microscopy · 2 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein1064—P39524
C—protein350—P25656

Ligands and binding sites

  • 2Y5 · (2R)-1-{[(R)-hydroxy{[(1r,2r,3r,4r,5s,6r)-2,3,5,6-tetrahydroxy-4-(phosphonooxy) cyclohexyl]oxy}phosphoryl]oxy}-3-(octadecanoyloxy) propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate · ligand · chains A
  • ACP · Phosphomethylphosphonic acid adenylate ester · ligand · chains A
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 6 copies · chains C
  • BMA · beta-D-mannopyranose · sugar · 2 copies · chains C
  • MG · Magnesium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 7OH7 · Cryo-EM structure of Drs2p-Cdc50p in the E1-AMPPCP state with PI4P bound · the same entry in another collection · chain A against A, TM-score 1.00
  • P25656 · AlphaFold monomer V2.0 prediction for cell division control protein 50 (P25656) · a predicted model of the same protein · chain C against A, TM-score 0.96
  • P39524 · AlphaFold monomer V2.0 prediction for probable phospholipid- transporting ATPase DRS2… · a predicted model of the same protein · chain A against A, TM-score 0.84

Analyse

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.