NADPH bound to the dehydrogenase domain of the bifunctional mannitol- 1-phosphate DEHYDROGENASE/PHOSPHATASE mtld-N374A from acinetobacter baumannii

Structure

x-ray diffraction · 2 distinct chains.

Ligands and binding sites

• NDP · Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate · ligand · 2 copies · chains A, B
• MG · Magnesium ion · metal · 2 copies · chains A, B
• K · Potassium ion · metal · chains A
• SO4 · Sulfate ion · ion · 6 copies · chains A, B
• CL · Chloride ion · ion · 2 copies · chains A, B
• EDO · 1,2-ethanediol · additive · 3 copies · chains A, B
• EPE · 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid · additive · 2 copies · chains A, B
• ACT · Acetate ion · additive · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

• 7OCT · NADPH bound to the dehydrogenase domain of the bifunctional mannitol-1-phosphate… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt D0C7J2
• Elsewhere: RCSB PDB 7OCT · PDBe 7OCT · UniProt D0C7J2