MolNFT v1 · #184074 · protein

K1K1, a potent recombinant minimal hepatocyte growth FACTOR/SCATTER factor mimic

7OCL · Hepatocyte growth factor alpha CHAIN,HEPATOCYTE growth…: “K1K1, a potent recombinant minimal hepatocyte growth FACTOR/SCATTER factor mimic”. X-ray diffraction, 1 pocket (best druggability 0.49). MolNFT v1 #184074 on GenesisL1: 3D…

PDB: 7OCL
Type: protein
Length: 336 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Hepatocyte growth factor alpha CHAIN,HEPATOCYTE growth factor alpha chain
UniProt: P14210
Pockets: 1 · best druggability 0.49

Structure

x-ray diffraction · 1 distinct chain · 4% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Hepatocyte growth factor alpha CHAIN,HEPATOCYTE growth factor alpha chain	protein	168	4% helix, 17% strand	P14210

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	193	0.49	0.76	31	empty

Interfaces

1 interface between chains.

A–B · 596 Å² buried · 19 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 12 disulfide (disulfide).

Compared structures

7OCL · K1K1, a potent recombinant minimal hepatocyte growth factor/scatter factor mimic · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P14210
Elsewhere: RCSB PDB 7OCL · PDBe 7OCL · UniProt P14210

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