MolNFT v1 · #184012 · protein
Crystal structure of pseudokinase cask in complex with compound 7
7OAJ: “Crystal structure of pseudokinase cask in complex with compound 7”. X-ray diffraction, 1 ligand (V6E). MolNFT v1 #184012 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7OAJ
- Type
- protein
- Length
- 1,189 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- O14936
- Ligands
- V6E
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 298 | — | O14936 |
| B, C, D | — | protein | 297 | — | O14936 |
Ligands and binding sites
- V6E · 4-(cyclopentylamino)-2-[(3,4-dichlorophenyl) methylamino]-N-[3-(2-oxidanylidenepyrrolidin-1-yl) propyl]pyrimidine-5-carboxamide · ligand · 4 copies · chains A, B, C, D
- EDO · 1,2-ethanediol · additive · 22 copies · chains A, B, C, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7OAJ · Crystal structure of pseudokinase CASK in complex with compound 7 · the same entry in another collection · chain D against D, TM-score 1.00
- O14936 · AlphaFold monomer V2.0 prediction for peripheral plasma membrane protein cask (O14936) · a predicted model of the same protein · chain C against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O14936
- Elsewhere: RCSB PDB 7OAJ · PDBe 7OAJ · UniProt O14936
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