MolNFT v1 · #183957 · protein

Nmhr light state structure at 300 us after photoexcitation determined by serial femtosecond crystallography (with extrapolated, dark and light dataset)

7O8K · Chloride pumping rhodopsin: “Nmhr light state structure at 300 us after photoexcitation determined by serial femtosecond crystallography…”. X-ray diffraction, 2 ligands (OLA, RET), 1 pocket (best druggability 0.73). MolNFT v1…

PDB: 7O8K
Type: protein
Length: 265 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Chloride pumping rhodopsin
UniProt: W8VZW3
Ligands: OLA, RET
Pockets: 1 · best druggability 0.73

Structure

x-ray diffraction · 1 distinct chain · 81% helix, 3% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Chloride pumping rhodopsin	protein	265	81% helix, 3% strand	W8VZW3

Ligands and binding sites

OLA · Oleic acid · ligand · 4 copies · chains A
RET · Retinal · ligand · chains A
OLC · (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate · additive · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	154	0.73	0.91	23	RET

Modifications

Observed in the structure: 1 cofactor (retinal Schiff base).

Compared structures

7O8K · NmHR light state structure at 300 us after photoexcitation determined by serial… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt W8VZW3
Elsewhere: RCSB PDB 7O8K · PDBe 7O8K · UniProt W8VZW3

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