MolNFT v1 · #183926 · protein
Crystal structure of the human HIPK3 kinase domain bound to abemaciclib
7O7J: “Crystal structure of the human HIPK3 kinase domain bound to abemaciclib”. X-ray diffraction, 1 ligand (6ZV). MolNFT v1 #183926 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7O7J
- Type
- protein
- Length
- 368 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q9H422
- Ligands
- 6ZV
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 368 | — | Q9H422 |
Ligands and binding sites
- 6ZV · N-{5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl}-5-fluoro-4-[4-fluoro-2-methyl-1-(propan-2-yl)-1H-benzimidazol-6-yl]pyrimidin-2-amine · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7O7J · Crystal structure of the human HIPK3 kinase domain bound to abemaciclib · the same entry in another collection · chain A against A, TM-score 1.00
- Q9H422 · AlphaFold monomer V2.0 prediction for homeodomain-interacting protein kinase 3 (Q9H422) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9H422
- Elsewhere: RCSB PDB 7O7J · PDBe 7O7J · UniProt Q9H422
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.