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UniProt Q9H422

Homeodomain-interacting protein kinase 3 (Q9H422)

Homeodomain-interacting protein kinase 3 (UniProt Q9H422), EC 2.7.11.1: 4 experimental structures on GenesisL1, 1 ligand bound, 3 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q9H422
Protein
Homeodomain-interacting protein kinase 3
EC
2.7.11.1
Experimental structures
4
Predicted models
0
Ligands
1
Pockets
3 · 1 record with a druggable one

Structures

4 records of Q9H422 in the MolNFT archive: 4 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
7O7ICrystal structure of the human HIPK3 kinase domainx-ray diffractionA——
7O7JCrystal structure of the human HIPK3 kinase domain bound to abemaciclibx-ray diffractionA6ZV3 (best 0.66)
7O7JCrystal structure of the human HIPK3 kinase domain bound to abemaciclibx-ray diffractionA6ZV—
Q9H422AlphaFold monomer V2.0 prediction for homeodomain-interacting protein kinase 3 (Q9H422)———

Ligands

  • 6ZV · N-{5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl}-5-fluoro-4-[4-fluoro-2-methyl-1-(propan-2-yl)-1H-benzimidazol-6-yl]pyrimidin-2-amine · in 2 records

Elsewhere

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