MolNFT v1 · #183771 · protein
Yeast 20S proteasome in complex with the covalently bound inhibitor B- lactone (2R,3S)-3-isopropyl-4-oxo-2-oxetane-carboxylate (ioc)
7O2L: “Yeast 20S proteasome in complex with the covalently bound inhibitor B- lactone…”. X-ray diffraction, 3 ligands (V08, MG, CL). MolNFT v1 #183771 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7O2L
- Type
- protein
- Length
- 6,334 residues
- Chains
- 28
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- A0A6L1BIF8, A0A6A5PXC6, A0A6A5Q273, P32379, A0A6A5PTH4, A0A6A5Q4M4, A0A6A5PYC9, A0A6A5Q449, A0A6L0YA22, A0A6A5Q0W2, A0A6V8RU78, A0A6A5Q0P3, P30657, A0A6L0ZSP2
- Ligands
- V08, MG, CL
Structure
x-ray diffraction · 14 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, O | — | protein | 250 | — | A0A6L1BIF8 |
| B, P | — | protein | 244 | — | A0A6A5PXC6 |
| C, Q | — | protein | 240 | — | A0A6A5Q273 |
| D, R | — | protein | 235 | — | P32379 |
| E, S | — | protein | 231 | — | A0A6A5PTH4 |
| F, T | — | protein | 243 | — | A0A6A5Q4M4 |
| G, U | — | protein | 241 | — | A0A6A5PYC9 |
| H, V | — | protein | 226 | — | A0A6A5Q449 |
| I, W | — | protein | 204 | — | A0A6L0YA22 |
| J, X | — | protein | 195 | — | A0A6A5Q0W2 |
| K, Y | — | protein | 212 | — | A0A6V8RU78 |
| L, Z | — | protein | 222 | — | A0A6A5Q0P3 |
| M, a | — | protein | 228 | — | P30657 |
| N, b | — | protein | 196 | — | A0A6L0ZSP2 |
Ligands and binding sites
- V08 · (2 {R},3 {S})-3-methanoyl-4-methyl-2-hydroxy-pentanoic acid · ligand · 6 copies · chains H, K, N, V, Y, b
- MG · Magnesium ion · metal · 8 copies · chains G, I, K, W, N, a, L, V, Y, Z
- CL · Chloride ion · ion · 2 copies · chains G, H, U, V
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7O2L · Yeast 20S proteasome in complex with the covalently bound inhibitor b-lactone… · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A6L1BIF8
- Every structure of UniProt A0A6A5PXC6
- Every structure of UniProt A0A6A5Q273
- Every structure of UniProt P32379
- Every structure of UniProt A0A6A5PTH4
- Every structure of UniProt A0A6A5Q4M4
- Every structure of UniProt A0A6A5PYC9
- Every structure of UniProt A0A6A5Q449
- Every structure of UniProt A0A6L0YA22
- Every structure of UniProt A0A6A5Q0W2
- Every structure of UniProt A0A6V8RU78
- Every structure of UniProt A0A6A5Q0P3
- Every structure of UniProt P30657
- Every structure of UniProt A0A6L0ZSP2
- Elsewhere: RCSB PDB 7O2L · PDBe 7O2L · UniProt A0A6L1BIF8 · UniProt A0A6A5PXC6 · UniProt A0A6A5Q273 · UniProt P32379 · UniProt A0A6A5PTH4 · UniProt A0A6A5Q4M4 · UniProt A0A6A5PYC9 · UniProt A0A6A5Q449 · UniProt A0A6L0YA22 · UniProt A0A6A5Q0W2 · UniProt A0A6V8RU78 · UniProt A0A6A5Q0P3 · UniProt P30657 · UniProt A0A6L0ZSP2
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