MolNFT v1 · #183753 · protein
X-ray structure of furin in complex with the guanylhydrazone-based inhibitor 4 (MI359)
7O22: “X-ray structure of furin in complex with the guanylhydrazone-based inhibitor 4 (MI359)”. X-ray diffraction, 5 ligands (UYW, NAG, CA). MolNFT v1 #183753 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7O22
- Type
- protein
- Length
- 464 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P09958
- Ligands
- UYW, NAG, CA, NA, CL
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 464 | — | P09958 |
Ligands and binding sites
- UYW · [azanyl-[(2E)-2-[[2-[(4-chlorophenyl) methoxy]phenyl]methylidene]hydrazinyl]methylidene]azan ium · ligand · chains A
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · chains A
- CA · Calcium ion · metal · 3 copies · chains A
- NA · Sodium ion · metal · 2 copies · chains A
- CL · Chloride ion · ion · chains A
- DMS · Dimethyl sulfoxide · additive · 4 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7O22 · X-ray structure of furin in complex with the guanylhydrazone-based inhibitor 4 (mi359) · the same entry in another collection · chain A against A, TM-score 1.00
- P09958 · AlphaFold monomer V2.0 prediction for furin (P09958) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P09958
- Elsewhere: RCSB PDB 7O22 · PDBe 7O22 · UniProt P09958
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.