Complex-B bound [fefe]-hydrogenase maturase hyde fromt. maritima (wild-type protein)

Structure

x-ray diffraction · 1 distinct chain · 42% helix, 13% strand (DSSP).

Ligands and binding sites

• CPS · 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate · ligand · 5 copies · chains A
• CYS · Cysteine · ligand · chains A
• FES · Fe2/s2 (inorganic) cluster · ligand · chains A
• SF4 · Iron/sulfur cluster · ligand · chains A
• SAH · S-adenosyl-L-homocysteine · ligand · chains A
• FE2 · Fe (II) ion · metal
• CMO · Carbon monoxide · ion · 2 copies · chains A
• H2S · Hydrosulfuric acid · ion · 2 copies · chains A
• CYN · Cyanide ion · ion · chains A
• IOD · Iodide ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Compared structures

• 7O1S · Complex-B bound [FeFe]-hydrogenase maturase HydE fromT. Maritima (Wild-type protein) · the same entry in another collection · chain A against A, TM-score 1.00
• Q9X0Z6 · AlphaFold monomer V2.0 prediction for [fefe] hydrogenase maturase subunit hyde (Q9X0Z6) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q9X0Z6
• Elsewhere: RCSB PDB 7O1S · PDBe 7O1S · UniProt Q9X0Z6