MolNFT v1 · #183616 · protein

Crystal structure of ALK in complex with FAB324

7NX3: “Crystal structure of ALK in complex with FAB324”. X-ray diffraction, 1 ligand (NAG). MolNFT v1 #183616 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7NX3
Type: protein
Length: 1,438 residues
Chains: 6
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: Q9UM73
Ligands: NAG

Structure

x-ray diffraction · 5 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	292	—	Q9UM73
B	—	protein	209	—	—
C, D	—	protein	216	—	—
E	—	protein	212	—	—
F	—	protein	293	—	Q9UM73

Ligands and binding sites

NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 8 copies · chains A, C, F, D

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7NX3 · Crystal structure of ALK in complex with Fab324 · the same entry in another collection · chain F against F, TM-score 1.00
Q9UM73 · AlphaFold monomer V2.0 prediction for ALK tyrosine kinase receptor (Q9UM73) · a predicted model of the same protein · chain F against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9UM73
Elsewhere: RCSB PDB 7NX3 · PDBe 7NX3 · UniProt Q9UM73

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