MolNFT v1 · #183581 · protein + DNA

Human pol kappa holoenzyme with wt PCNA

7NV0: “Human pol kappa holoenzyme with wt PCNA”. Electron microscopy, 1 ligand (TTP). MolNFT v1 #183581 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7NV0
Type: protein + DNA
Length: 1,233 residues
Chains: 6
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: Q9UBT6, P12004
Ligands: TTP

Structure

electron microscopy · 6 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	430	—	Q9UBT6
B	—	protein	248	—	P12004
C	—	protein	253	—	P12004
D	—	protein	249	—	P12004
P	—	dna	25	—	—
T	—	dna	28	—	—

Ligands and binding sites

TTP · Thymidine-5'-triphosphate · ligand · chains A, P, T

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7NV0 · Human Pol Kappa holoenzyme with wt PCNA · the same entry in another collection · chain C against C, TM-score 1.00
Q9UBT6 · AlphaFold monomer V2.0 prediction for DNA polymerase kappa (Q9UBT6) · a predicted model of the same protein · chain A against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9UBT6
Every structure of UniProt P12004
Elsewhere: RCSB PDB 7NV0 · PDBe 7NV0 · UniProt Q9UBT6 · UniProt P12004

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.