MolNFT v1 · #183222 · protein + RNA
Cryoem structure of disease related M854K MDA5-dsrna filament in complex with ADP-ALF4(MAJOR class)
7NIQ: “Cryoem structure of disease related M854K MDA5-dsrna filament in complex with ADP-ALF4(MAJOR class)”. Electron microscopy, 3 ligands (ADP, ALF, ZN). MolNFT v1 #183222 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7NIQ
- Type
- protein + RNA
- Length
- 701 residues
- Chains
- 3
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q8R5F7
- Ligands
- ADP, ALF, ZN
Structure
electron microscopy · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | — | protein | 673 | — | Q8R5F7 |
| C | — | rna | 14 | — | — |
| G | — | rna | 14 | — | — |
Ligands and binding sites
- ADP · Adenosine-5'-diphosphate · ligand · chains B
- ALF · Tetrafluoroaluminate ion · ligand · chains B
- ZN · Zinc ion · metal · chains B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7NIQ · CryoEM structure of disease related M854K MDA5-dsRNA filament in complex with… · the same entry in another collection · chain B against B, TM-score 1.00
- Q8R5F7 · AlphaFold monomer V2.0 prediction for interferon-induced helicase C domain-containing… · a predicted model of the same protein · chain B against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8R5F7
- Elsewhere: RCSB PDB 7NIQ · PDBe 7NIQ · UniProt Q8R5F7
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