MolNFT v1 · #182861 · protein

Crystal structure of inhibitor-free HIV-1 PRS17 revertant mutant PRS17 V48G

7N6T · Protease: “Crystal structure of inhibitor-free HIV-1 PRS17 revertant mutant PRS17 V48G”. X-ray diffraction, 1 pocket (best druggability 0.57). MolNFT v1 #182861 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7N6T
Type: protein
Length: 198 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protease
EC: 3.4.23.16
UniProt: P03367
Pockets: 1 · best druggability 0.57

Structure

x-ray diffraction · 1 distinct chain · 6% helix, 54% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Protease (EC 3.4.23.16)	protein	99	6% helix, 54% strand	P03367

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	445	0.57	0.73	41	empty

Interfaces

1 interface between chains.

A–B · 1556 Å² buried · 34 hydrogen bonds · protein-protein

Compared structures

7N6T · Crystal structure of inhibitor-free HIV-1 PRS17 revertant mutant PRS17 V48G · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P03367
Elsewhere: RCSB PDB 7N6T · PDBe 7N6T · UniProt P03367

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