MolNFT v1 · #182585 · protein
Cryo-EM structure of broadly neutralizing V2-apex-targeting antibody J038 in complex with HIV-1 env
7MXD: “Cryo-EM structure of broadly neutralizing V2-apex-targeting antibody J038 in complex with HIV-1 env”. Electron microscopy, 4 ligands (NAG, MAN, BMA). MolNFT v1 #182585 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7MXD
- Type
- protein
- Length
- 3,519 residues
- Chains
- 14
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- I6NF57
- Ligands
- NAG, MAN, BMA, PO4
Structure
electron microscopy · 6 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, F, G | — | protein | 472 | — | I6NF57 |
| C, J, S | — | protein | 216 | — | — |
| D, K, U | — | protein | 204 | — | — |
| X | — | protein | 221 | — | — |
| Y | — | protein | 214 | — | — |
| B, I, H | — | protein | 136 | — | I6NF57 |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 108 copies · chains A, C, D, B, I, F, X, J, K, G, U, H, S
- MAN · alpha-D-mannopyranose · sugar · 27 copies · chains A, J, D, F, S, K, X, G, C, U
- BMA · beta-D-mannopyranose · sugar · 8 copies · chains D, X
- PO4 · Phosphate ion · ion · 3 copies · chains A, F, G
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7MXD · Cryo-EM structure of broadly neutralizing V2-apex-targeting antibody J038 in complex with… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt I6NF57
- Elsewhere: RCSB PDB 7MXD · PDBe 7MXD · UniProt I6NF57
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