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UniProt I6NF57

Envelope glycoprotein gp41 (I6NF57)

Envelope glycoprotein gp41 (UniProt I6NF57): 4 experimental structures on GenesisL1, 5 ligands bound, 35 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
I6NF57
Protein
Envelope glycoprotein gp41
Experimental structures
4
Predicted models
0
Ligands
5
Pockets
35 · 2 records with a druggable one

Structures

4 records of I6NF57 in the MolNFT archive: 4 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
7MXDCryo-EM structure of broadly neutralizing V2-apex-targeting antibody J038 in complex with HIV-1 envelectron microscopyA, F, G, B, I, HNAG, MAN, PO4—
7N28Cryo-EM structure of broadly neutralizing V2-apex-targeting antibody J033 in complex with HIV-1 Envelectron microscopyA, F, G, M, B, NNAG, BMA, MAN, PO415 (best 0.80)
7N28Cryo-EM structure of broadly neutralizing V2-apex-targeting antibody J033 in complex with HIV-1 envelectron microscopyA, F, G, M, B, NNAG, BMA, MAN, PO4—
9BIOStructure of VRC44.01 Fab in complex with 3BNC117-purified C1080.c3 RnS SOSIP.664 HIV-1 Env trimerelectron microscopyB, G, A, C, J, KNAG, FUC, BMA, MAN, PO420 (best 0.81)

Ligands

  • MAN · alpha-D-mannopyranose · in 4 records
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 4 records
  • PO4 · Phosphate ion · in 4 records
  • BMA · beta-D-mannopyranose · in 3 records
  • FUC · alpha-L-fucopyranose · in 1 record

Elsewhere

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