MolNFT v1 · #182576 · protein
Plk-1 polo-box domain in complex with a high affinity macrocycle synthesized using a novel glutamic acid analog
7MX1: “Plk-1 polo-box domain in complex with a high affinity macrocycle synthesized using a novel glutamic acid…”. X-ray diffraction, 2 ligands (ACE, ZOY). MolNFT v1 #182576 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7MX1
- Type
- protein
- Length
- 452 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P53350
- Ligands
- ACE, ZOY
Structure
x-ray diffraction · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 220 | — | P53350 |
| B | — | protein | 222 | — | P53350 |
| C, E | — | protein | 5 | — | — |
Ligands and binding sites
- ACE · Acetyl group · ligand · 2 copies · chains A, C, B, E
- ZOY · N-[(4S)-4,5-diamino-5-oxopentyl]-10-phenyldecanamide · ligand · 2 copies · chains A, C, B, E
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7MX1 · PLK-1 polo-box domain in complex with a high affinity macrocycle synthesized using a… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P53350
- Elsewhere: RCSB PDB 7MX1 · PDBe 7MX1 · UniProt P53350
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