MolNFT v1 · #182393 · protein

Cryo-EM structure of the yeast cadmium factor 1 protein (YCF1P)

7MPE · Metal resistance protein YCF1: “Cryo-EM structure of the yeast cadmium factor 1 protein (YCF1P)”. Electron microscopy, 18 pockets (best druggability 0.83). MolNFT v1 #182393 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 7MPE
Type: protein
Length: 1,428 residues
Chains: 1
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Metal resistance protein YCF1
EC: 7.2.2.2, 7.6.2.3
UniProt: P39109
Pockets: 18 · best druggability 0.83

Structure

electron microscopy · 1 distinct chain · 58% helix, 8% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Metal resistance protein YCF1 (EC 7.2.2.2, 7.6.2.3)	protein	1428	58% helix, 8% strand	P39109

Pockets

18 pockets found on a 1 Å grid, 9 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	747	0.83	0.86	64	empty
2	568	0.77	0.83	48	empty
3	177	0.68	0.87	34	empty
4	673	0.65	0.74	90	empty
5	464	0.65	0.77	55	empty

Compared structures

7MPE · Cryo-EM structure of the yeast cadmium factor 1 protein (Ycf1p) · the same entry in another collection · chain A against A, TM-score 1.00
P39109 · AlphaFold monomer V2.0 prediction for metal resistance protein YCF1 (P39109) · a predicted model of the same protein · chain A against A, TM-score 0.93

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P39109
Elsewhere: RCSB PDB 7MPE · PDBe 7MPE · UniProt P39109

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