UniProt P39109
Metal resistance protein YCF1 (P39109)
Metal resistance protein YCF1 (UniProt P39109), EC 7.2.2.2, 7.6.2.3: 9 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 129 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P39109
- Protein
- Metal resistance protein YCF1
- EC
- 7.2.2.2, 7.6.2.3
- Experimental structures
- 9
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 129 · 7 records with a druggable one
Structures
10 records of P39109 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7M68 | E1435Q YCF1 mutant in inward-facing narrow conformation | electron microscopy | A | — | — |
| 7M69 | E1435Q Ycf1 mutant in inward-facing wide conformation | electron microscopy | A | — | 20 (best 0.84) |
| 7M69 | E1435Q YCF1 mutant in inward-facing wide conformation | electron microscopy | A | — | — |
| 7MPE | Cryo-EM structure of the yeast cadmium factor 1 protein (Ycf1p) | electron microscopy | A | — | 18 (best 0.83) |
| 7MPE | Cryo-EM structure of the yeast cadmium factor 1 protein (YCF1P) | electron microscopy | A | — | — |
| 8SG4 | E1435Q Ycf1 mutant in dephosphorylated state | electron microscopy | A | — | 17 (best 0.90) |
| 8SQ0 | Cleaved Ycf1p Dimer in the IFwide-beta conformation | electron microscopy | A, B | PTY, GP7, LPP | 20 (best 0.84) |
| 8SQL | Cleaved Ycf1p Monomer in the Beta Conformation | electron microscopy | A | PTY | 16 (best 0.85) |
| 8SQM | Cleaved Ycf1p Monomer in the IFwide-alpha conformation | electron microscopy | A | 8PE | 18 (best 0.84) |
| P39109 | AlphaFold monomer V2.0 prediction for metal resistance protein YCF1 (P39109) | predicted | A | — | 20 (best 0.82) |
Ligands
- PTY · Phosphatidylethanolamine · in 2 records
- 8PE · (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl octadecanoate · in 1 record
- GP7 · (1R)-2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(pentadecanoyloxy)methyl]ethyl (12E)-hexadeca-9,12-dienoate · in 1 record
- LPP · 2-(hexadecanoyloxy)-1-[(phosphonooxy)methyl]ethyl hexadecanoate · in 1 record
Experiment against prediction
- 8SQM chain A against the predicted model P39109: TM-score 0.96, RMSD 2.64 Å
- 7M69 chain A against the predicted model P39109: TM-score 0.94, RMSD 3.06 Å
- 7M69 chain A against the predicted model P39109: TM-score 0.94, RMSD 3.06 Å
- 7MPE chain A against the predicted model P39109: TM-score 0.93, RMSD 3.49 Å
- 7MPE chain A against the predicted model P39109: TM-score 0.93, RMSD 3.49 Å
- 8SQ0 chain B against the predicted model P39109: TM-score 0.93, RMSD 3.55 Å
- 8SQ0 chain A against the predicted model P39109: TM-score 0.93, RMSD 3.55 Å
- 8SG4 chain A against the predicted model P39109: TM-score 0.93, RMSD 3.19 Å
- 8SQL chain A against the predicted model P39109: TM-score 0.92, RMSD 3.79 Å
- 7M68 chain A against the predicted model P39109: TM-score 0.91, RMSD 3.87 Å
Elsewhere
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